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局部照射成功治疗血管免疫母细胞性淋巴结病伴蛋白异常血症

Successful treatment of angioimmunoblastic lymphadenopathy with dysproteinemia by local irradiation.

作者信息

Okamura H, Misawa T

机构信息

Department of Otolaryngology, Fukushima Medical College, Japan.

出版信息

ORL J Otorhinolaryngol Relat Spec. 1998 Jul-Aug;60(4):233-5. doi: 10.1159/000027601.

DOI:10.1159/000027601
PMID:9646314
Abstract

We report an 85-year-old man presenting with angioimmunoblastic lymphadenopathy with dysproteinemia (AILD) of the palatine tonsil with cervical and axillary lymph node enlargement, pleural effusion and hypergammaglobulinemia. The patient was treated in Internal Medicine with combined chemotherapy with steroids which resulted in a complete remission. However, he returned almost 1 year later with an ulcerative lesion in the left palatine tonsil, with no lymph node involvement. Considering that the patient was an elderly person, chemotherapy had been administered during the initial admission, tumor cells appeared to originate from T cells and relapse occurred only in the local lesion, the lesion was treated by local irradiation using 60Co at a dose of 40 Gy, which produced a complete resolution. Radiotherapy appeared to be effective for the treatment of localized lesions of AILD.

摘要

我们报告了一名85岁男性,患有腭扁桃体血管免疫母细胞性淋巴结病伴蛋白异常血症(AILD),伴有颈部和腋窝淋巴结肿大、胸腔积液和高球蛋白血症。该患者在内科接受了联合化疗及类固醇治疗,实现了完全缓解。然而,近1年后他因左侧腭扁桃体出现溃疡性病变再次就诊,无淋巴结受累。考虑到患者为老年人,初次入院时已接受化疗,肿瘤细胞似乎起源于T细胞且仅在局部病变复发,遂采用60Co以40 Gy的剂量对病变进行局部照射治疗,病变完全消退。放疗似乎对AILD的局限性病变治疗有效。

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