Terui T, Tagami H
Department of Dermatology, Tohoku University School of Medicine, Seiryomachi 1-1, Aoba-ku, Sendai 980-8574, Japan.
Eur J Dermatol. 1998 Mar;8(2):127-30.
We report a case of facial annular lesions in a non-diabetic, Japanese woman aged 78, the histopathological study of which showed noncaseating, epithelioid cell granuloma with multinucleated giant cells. Together with the aberrant laboratory data, these clinical and histopathological findings were considered to be compatible with those of sarcoidosis, but elastic tissue stain disclosed the existence of elastolytic changes which were clinically and histopathologically similar to those found in actinic granuloma or annular elastolytic giant cell granuloma. Based on a review of the literature, we believe that several annular elastolytic granulomatous diseases of the face form a disease spectrum, some of which are identified with intermediate features of these three diseases.
我们报告一例78岁非糖尿病日本女性面部环状皮损病例，其组织病理学研究显示为非干酪样上皮样细胞肉芽肿伴多核巨细胞。结合异常的实验室数据，这些临床和组织病理学表现被认为与结节病相符，但弹性组织染色显示存在弹性组织溶解改变，其临床和组织病理学特征与光化性肉芽肿或环状弹性组织溶解性巨细胞肉芽肿相似。基于文献回顾，我们认为面部几种环状弹性组织溶解性肉芽肿性疾病构成一个疾病谱，其中一些具有这三种疾病的中间特征。
