Becker M J, Becker A E
Hum Pathol. 1976 Sep;7(5):495-504. doi: 10.1016/s0046-8177(76)80098-6.
The presence of fat in the fetal zone of the adrenal cortex in the stillborn macerated fetus is indicative of the mode of intrauterine death. Three basic patterns are recognized. In the type I pattern there is only a scant amount of fat, close to the medullary zone. In the type II pattern fat is more widespread and is present in many more cells of the fetal zone. The type III pattern reflects a massive fatty change of almost all cells throughout the fetal cortical zone. Correlation of the three fat patterns with the pathology of the placenta and clinical data relevant to the etiology of intrauterine death has led to the following conclusions. The type I fat pattern is indicative of an acute mode of death, the type II pattern is indicative of a more prolonged period of intrauterine deterioration prior to death, whereas the type III pattern is indicative of a chronic mode of death. Determination of the fat patterns in the fetal zone of the adrenal cortex can be helpful when the clinician is confronted with the problem of fetal death, especially when maceration may hamper more detailed pathologic studies.
死产浸软胎儿肾上腺皮质胎儿带中脂肪的存在表明宫内死亡方式。已识别出三种基本模式。在I型模式中，仅在靠近髓质带处有少量脂肪。在II型模式中，脂肪分布更广，存在于胎儿带的更多细胞中。III型模式反映了整个胎儿皮质带几乎所有细胞的大量脂肪变性。将这三种脂肪模式与胎盘病理学以及与宫内死亡病因相关的临床数据进行关联后得出了以下结论。I型脂肪模式表明急性死亡方式，II型模式表明死亡前宫内恶化时间更长，而III型模式表明慢性死亡方式。当临床医生面临胎儿死亡问题时，尤其是浸软可能妨碍更详细的病理研究时，确定肾上腺皮质胎儿带中的脂肪模式可能会有所帮助。
