Spanĕl P, Davies S, Smith D
J. Heyrovsky Institute of Physical Chemistry, Academy of Sciences of the Czech Republic, Prague, Czech Republic.
Rapid Commun Mass Spectrom. 1998;12(12):763-66. doi: 10.1002/(SICI)1097-0231(19980630)12:12<763::AID-RCM229>3.0.CO;2-S.
We show how our selected ion flow tube mass spectrometric technique for trace gas analysis can be used to determine the concentrations of ammonia in alveolar breath from single exhalations using both H30+ and 02+ precursor ions for chemical ionization. Thus, data are presented of the alveolar ammonia concentrations in the breath of six healthy volunteers following the ingestion of a liquid protein meal, which show that consistent values are obtained using these two precursor ions. Alveolar breath ammonia concentrations (which range from 200 to 1750 ppb in these individuals) are compared with those obtained from bag samples of breath from the same individuals.
我们展示了如何使用我们选定的用于痕量气体分析的离子流管质谱技术，通过使用H30+和02+前体离子进行化学电离，来测定单次呼气时肺泡气中氨的浓度。因此，本文给出了六名健康志愿者摄入液体蛋白质餐后呼出气体中肺泡氨浓度的数据，这些数据表明使用这两种前体离子可获得一致的值。将这些个体（肺泡气氨浓度范围为200至1750 ppb）的肺泡气氨浓度与从同一受试者的呼气袋样品中获得的浓度进行了比较。
