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葡萄糖对下丘脑内侧与外侧矢状旁切口前后摄食中枢活动的影响。

Effect of glucose on the activity of feeding centres before and after parasagittal cuts between medial and lateral hypothalamus.

作者信息

Bhattacharyya S P, Nayar U, Anand B K

出版信息

Indian J Physiol Pharmacol. 1976 Apr-Jun;20(2):47-52.

PMID:965075
Abstract

Intracarotid administration of isotonic glucose (0.5 ml of 5.4%) in the starving albino rats produced an increase in the multiunit activity (MUA) of ventromedial hypothalamus (satiety centre) and a decrease in the MUA of the lateral hypothalamic area (feeding centre). Intracarotid infusion of normal saline did not change the MUA of any of these centres. Parasagittal knife cuts placed in between the satiety and feeding centres did not affect the responsiveness of these centres to glucose administration as indicated by the recorded multiunit activity.

摘要

给饥饿的白化病大鼠颈内注射等渗葡萄糖(0.5毫升5.4%的葡萄糖溶液),可使腹内侧下丘脑(饱食中枢)的多单位活动(MUA)增加,而外侧下丘脑区域(摄食中枢)的MUA减少。颈内注射生理盐水不会改变这些中枢中任何一个的MUA。如记录的多单位活动所示,在饱食中枢和摄食中枢之间进行矢状旁切,并不影响这些中枢对葡萄糖注射的反应性。

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Indian J Physiol Pharmacol. 1976 Apr-Jun;20(2):47-52.
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