Adams E
Int J Pept Protein Res. 1976;8(5):503-16. doi: 10.1111/j.1399-3011.1976.tb02531.x.
Synthesis and properties are reported for a number of peptides and related derivatives of 3-hydroxy-L-proline and 4-hydroxyl-L-proline. These were made for several different purposes, namely, sythesis of N-acetyl-O-tosyl-4-hydroxy-L-proline amide as a model for chemical reduction of peptide-bound hydroxyproline, synthesis of tripeptides with the sequence glycyl-4-hydroxy-L-hydroxy-L-prolyl-X, synthesis of the naturally occurring sequence, glycyl-3-hydroxy-L-prolyl-4-hydroxy-L-proline, and monomers for polymerization to yield the sequence -glycyl-prolyl-4-hydroxy-L-prolyl-.
报道了多种3-羟基-L-脯氨酸和4-羟基-L-脯氨酸的肽及相关衍生物的合成与性质。制备这些化合物有几个不同的目的，即合成N-乙酰基-O-甲苯磺酰基-4-羟基-L-脯氨酸酰胺作为肽结合羟脯氨酸化学还原的模型，合成序列为甘氨酰-4-羟基-L-羟基-L-脯氨酰-X的三肽，合成天然存在的序列甘氨酰-3-羟基-L-脯氨酰-4-羟基-L-脯氨酸，以及用于聚合以产生序列-甘氨酰-脯氨酰-4-羟基-L-脯氨酰-的单体。
