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恒河猴的选择行为:可卡因与食物

Choice behavior in rhesus monkeys: cocaine versus food.

作者信息

Aigner T G, Balster R L

出版信息

Science. 1978 Aug 11;201(4355):534-5. doi: 10.1126/science.96531.

DOI:10.1126/science.96531
PMID:96531
Abstract

Rhesus monkeys were allowed to choose between intravenous injections of cocaine and food reinforcement for lever pressing. A choice trial was available every 15 minutes continuously for 8 days. The animals chose cocaine almost exclusively, which resulted in high cocaine intake, decreased food intake, weight loss, and marked behavioral toxicity. The study provides evidence of the reinforcing efficacy of cocaine.

摘要

恒河猴可以在静脉注射可卡因和按压杠杆获取食物强化物之间进行选择。每隔15分钟持续进行一次选择试验,共持续8天。这些动物几乎只选择可卡因,这导致可卡因摄入量高、食物摄入量减少、体重减轻以及明显的行为毒性。该研究提供了可卡因强化效力的证据。

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