Mordarska H, Zakrzewska-Czerwiñska J, Paściak M, Szponar B, Rowiñski S
Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław.
FEMS Immunol Med Microbiol. 1998 May;21(1):47-55. doi: 10.1111/j.1574-695X.1998.tb01148.x.
An opportunistic actinomycete was isolated as the only etiological agent of a severe, suppurative pulmonary infection. The strain was rapidly recognised as Nocardiopsis by the taxonomically important and immunologically active glycolipid markers (G1 and G2). Identification of the clinical isolate, from a group of actinomycetes mainly known as soil habitants, was definitely proved by chemotaxonomic studies (cell wall/sugar, phospholipid and fatty acid types) as well as by genomic data (GC content, DNA-DNA reassociation). The level of DNA-DNA homology of the clinical actinomycete, in comparison with other reference members of this genus, revealed the highest (88%) relatedness to Nocardiopsis dassonvillei. The results confirmed the value and generic specificity of glycolipid markers from Nocardiopsis, the first time used for rapid recognition of a clinical strain causing a nocardiosis-like disease.
