Tremblay C, Gaudreau C
Département de Microbiologie Médicale et Infectiologie, Centre Hospitalier de l'Université de Montréal, Québec, Canada.
Antimicrob Agents Chemother. 1998 Jul;42(7):1847-9. doi: 10.1128/AAC.42.7.1847.
The susceptibilities of 59 Campylobacter fetus subsp. fetus isolates to eight antibiotics were studied by the agar dilution, E-test, and disk diffusion methods. None of the isolates were beta-lactamase producers. All were susceptible to ampicillin, gentamicin, imipenem, and meropenem as determined by the three methods, with MICs at which 90% of the isolates are inhibited (MIC90s) (determined by agar dilution) of 2, 1, < or = 0.06, and 0.12 microgram/ml, respectively. Twenty-seven percent of the isolates were resistant to tetracycline, with complete agreement between the agar dilution and disk diffusion results. The MIC90s determined by agar dilution were 2 micrograms/ml for erythromycin, 1 microgram/ml for ciprofloxacin, and 8 micrograms/ml for cefotaxime.
采用琼脂稀释法、E-test法和纸片扩散法,研究了59株胎儿弯曲菌胎儿亚种分离株对8种抗生素的敏感性。所有分离株均不产生β-内酰胺酶。三种方法均表明,所有分离株对氨苄西林、庆大霉素、亚胺培南和美罗培南敏感,通过琼脂稀释法测定的90%分离株被抑制时的最低抑菌浓度(MIC90)分别为2、1、≤0.06和0.12微克/毫升。27%的分离株对四环素耐药,琼脂稀释法和纸片扩散法的结果完全一致。通过琼脂稀释法测定的红霉素MIC90为2微克/毫升,环丙沙星为1微克/毫升,头孢噻肟为8微克/毫升。