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空肠弯曲菌胎儿亚种对20种抗菌药物的敏感性。

Susceptibility of Campylobacter fetus subsp. jejuni to twenty antimicrobiol agents.

作者信息

Walder M

出版信息

Antimicrob Agents Chemother. 1979 Jul;16(1):37-9. doi: 10.1128/AAC.16.1.37.

Abstract

One hundred recent clinical isolates of Campylobacter fetus subsp. jejuni were tested by an agar dilution technique for susceptibility to each of 20 antimicrobial agents. Doxycycline and gentamicin were the most active of the drugs examined, inhibiting all strains at concentrations achievable in serum. Although the median minimal inhibitory concentration of erythromycin was low, 8% of the isolates were highly resistant. All isolates of Campylobacter fetus subsp. jejuni were relatively resistant to the beta-lactam antibiotics. Some strains were highly resistant to metronidazole and tinidazole.

摘要

采用琼脂稀释法对100株空肠弯曲菌胎儿亚种近期临床分离株进行了20种抗菌药物的敏感性测试。强力霉素和庆大霉素是所检测药物中活性最强的,在血清可达到的浓度下能抑制所有菌株。虽然红霉素的中位最低抑菌浓度较低,但8%的分离株具有高度耐药性。所有空肠弯曲菌胎儿亚种分离株对β-内酰胺类抗生素相对耐药。一些菌株对甲硝唑和替硝唑高度耐药。

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