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来自伞房花弗吉尼亚木(蔷薇科)的肿瘤抑制因子。

Tumor inhibitory agents from Vauquelinia corymbosa (Rosaceae).

作者信息

Trumbull E R, Bianchi E, Eckert D J, Wiedhopf R M, Cole J R

出版信息

J Pharm Sci. 1976 Sep;65(9):1407-8. doi: 10.1002/jps.2600650938.

Abstract

The chloroform extract of Vauquelinia corymbosa Correa has shown activity against the P-388 lymphocytic leukemia test system. The constituents responsible for this activity were identified as uvaol, ursolic acid, and betulinic acid. Their identity was proven by melting point; mixed melting point; elemental analysis; IR, PMR, and mass spectra; and preparation of derivatives.

摘要

伞房花瓦奎木(Vauquelinia corymbosa Correa)的氯仿提取物已显示出对P - 388淋巴细胞白血病测试系统有活性。负责此活性的成分被鉴定为羽扇豆醇、熊果酸和桦木酸。它们的身份通过熔点、混合熔点、元素分析、红外光谱、核磁共振氢谱和质谱以及衍生物的制备得以证明。

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