De Vos M, De Keyser F, Mielants H, Cuvelier C, Veys E
Department of Gastroenterology, University Hospital, Gent, Belgium.
Aliment Pharmacol Ther. 1998 May;12(5):397-404. doi: 10.1046/j.1365-2036.1998.00325.x.
The intestinal and articular systems are closely linked in inflammatory bowel disease. Clinical and immunological studies support an important aetio-pathogenetic link between intestinal and articular inflammation. There is increasing evidence for a negative link between bone mass density and intestinal inflammation. This paper will focus on the prevalence, aetio-pathogenesis and treatment of arthritis (peripheral, sacroiliitis and spondylitis) and osteoporosis in inflammatory bowel disease.
在炎症性肠病中，肠道系统和关节系统紧密相连。临床和免疫学研究支持肠道炎症与关节炎症之间存在重要的病因 - 发病机制联系。越来越多的证据表明骨密度与肠道炎症之间存在负相关联系。本文将聚焦于炎症性肠病中关节炎（外周性、骶髂关节炎和脊柱炎）和骨质疏松症的患病率、病因发病机制及治疗。
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