Waiser J, Budde K, Schreiber M, Peibst O, Koch U, Böhler T, Höffken B, Hauser I, Neumayer H H
Department of Internal Medicine-Nephrology, Charité, Humboldt University, Berlin, Germany.
Transpl Int. 1998;11 Suppl 1:S42-5. doi: 10.1007/s001470050423.
The improved prognosis and survival statistics of both renal transplantation and dialysis have focused attention on the quality of life offered by these treatments. Using a standardized questionnaire, we assessed the quality of life of 612 patients undergoing renal replacement therapy at our center. Of these patients, 359 had been transplanted and 253 patients were on dialysis. Concerning the sociodemographic data, only the time on specific treatment was longer in dialysis patients than in transplanted patients (49.2 versus 55.6 months, P < 0.05). Most complaints were more common in dialysis patients than in transplanted patients. Only the side effects of medication were seen more in transplanted patients (P < 0.005). Life satisfaction was higher in transplanted patients than in dialysis patients. Dialysis patients were more anxious (P < 0.05) and more depressed (P < 0.001) than transplanted patients. Transplanted patients also felt that they had more social support than did dialysis patients. Overall life quality was almost equal between patients on hemodialysis and patients on peritoneal dialysis, and between patients on the waiting list for transplantation and those not on the waiting list. Despite a significantly better quality of life after renal transplantation, the percentage of patients working remained unchanged. (57.5% versus 57.8%, P = n.s.). We conclude that despite an improved quality of life after renal transplantation, these patients are economically not more productive than patients on dialysis.
肾移植和透析的预后及生存统计数据的改善,使人们将关注焦点放在了这些治疗方式所带来的生活质量上。我们使用标准化问卷,对在本中心接受肾脏替代治疗的612例患者的生活质量进行了评估。其中,359例接受了移植,253例接受透析治疗。关于社会人口统计学数据,仅透析患者的特定治疗时间比移植患者更长(49.2个月对55.6个月,P<0.05)。大多数不适症状在透析患者中比移植患者更常见。仅移植患者的药物副作用更为多见(P<0.005)。移植患者的生活满意度高于透析患者。透析患者比移植患者更焦虑(P<0.05)、更抑郁(P<0.001)。移植患者也感觉自己比透析患者获得了更多的社会支持。血液透析患者和腹膜透析患者之间,以及移植等待名单上的患者和未在等待名单上的患者之间,总体生活质量几乎相等。尽管肾移植后生活质量显著改善,但工作患者的比例并未改变(57.5%对57.8%,P无统计学意义)。我们得出结论,尽管肾移植后生活质量有所提高,但这些患者在经济上并不比透析患者更具生产力。