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乙醇诱导的高脂血症(齐夫综合征)中红细胞膜脂质的变化(作者译)

[Changes of erythrocyte membrane lipids in ethanol induced hyperlipidemia (Zieve's syndrome) (author's transl)].

作者信息

Schubotz R, Goebel K M, Kaffarnik H

出版信息

Klin Wochenschr. 1976 Sep 1;54(17):827-33. doi: 10.1007/BF01469304.

Abstract

In 11 patients with alcohol-induced hyperlipemia, of whom 6 showed a Zieve Syndrome increased phospholipids, triglycerides and total cholesterol were found in the red cells stromal. The gasliquid chromatographic analysis of the phospholipid fatty acids showed increased contents of saturated and monounsaturated fatty acids C 16-C 18 smaller contents of longchain highly unsaturated fatty acids. The changes in the fatty acid pattern mainly occurred in patients with Zieve Syndrome and could be important for the mechanism of the hemolytic anemia. Theses findings could be in connexion with vitamin E deficiency.

摘要

在11例酒精性高脂血症患者中,其中6例表现为齐夫综合征,红细胞基质中磷脂、甘油三酯和总胆固醇增加。磷脂脂肪酸的气液色谱分析显示,饱和脂肪酸和单不饱和脂肪酸C16 - C18含量增加,长链高度不饱和脂肪酸含量减少。脂肪酸模式的变化主要发生在齐夫综合征患者中,可能对溶血性贫血的机制很重要。这些发现可能与维生素E缺乏有关。

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