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[乌克兰森林草原地带的虫媒病毒及虫媒病毒感染]

[Arboviruses and arbovirus infections in the forest steppe zone of Ukraine].

作者信息

Lozyns'kyĭ I M, Vynohrad I A

机构信息

Research Institute of Epidemiology and Hygiene, Lviv, Ministry of Public Health of Ukraine.

出版信息

Mikrobiol Z. 1998 Mar-Apr;60(2):49-60.

PMID:9670754
Abstract

New active natural foci of the tick-borne encephalitis, West Nile, California serologic group (CSG) and Batai viruses have been identified as a result of comprehensive virologic and serologic investigations in the forest-steppe zone of Ukraine. These observations were confirmed by the results of these pathogens study and identification of the corresponding antigens in natural biological substrates and in the blood of ill people. Several human pathogenetic viruses, including Inko, Snow hoc hare with CSG and Crimean hemorrhagic fever were found for the first time in the forest-steppe zone. Viruses populations circulating there are heterogeneous according to their genetic properties. New data concerning their ecology were obtained. A close etiological relation between the acute seasonal febrile diseases and the above mentioned arboviruses was found. Arboviral infections from 23.6% of the total amount of spring-summer-autumn febrile diseases. The West Nile fever (53.1%) is the leading arboviral infection in the forest-steppe zone. A quarter of all arboviral infections is represented by tick-borne encephalitis. Diagnostic preparations have been made and the available methods of laboratory diagnostics of the arboviral infections have been improved.

摘要

通过在乌克兰森林草原地带开展的全面病毒学和血清学调查,已发现蜱传脑炎、西尼罗河病毒、加利福尼亚血清群(CSG)病毒和巴泰病毒的新的活跃自然疫源地。对这些病原体的研究结果以及在天然生物基质和病人血液中鉴定出相应抗原,证实了这些观察结果。首次在森林草原地带发现了几种人类致病病毒,包括因科病毒、带有CSG的雪兔病毒和克里米亚出血热病毒。在那里传播的病毒种群在遗传特性上具有异质性。获得了有关它们生态学的新数据。发现急性季节性发热疾病与上述虫媒病毒之间存在密切的病因关系。虫媒病毒感染占春夏秋三季发热疾病总量的23.6%。西尼罗河热(53.1%)是森林草原地带主要的虫媒病毒感染。所有虫媒病毒感染中有四分之一由蜱传脑炎构成。已制备了诊断制剂,并改进了现有的虫媒病毒感染实验室诊断方法。

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