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Synthesis, structural characterization and antimicrobial studies of 2,4-pentanedione derivatives. Part I.

作者信息

Varadarajan A, Utekar S S, Malve S P

机构信息

Department of Chemistry, Institute of Science, Mumbai, India.

出版信息

Acta Pol Pharm. 1998 Mar-Apr;55(2):137-41.

PMID:9673154
Abstract

The title compounds have been synthesized in good yields by the interaction of 2,3,4-pentanetrione-3-oxime with ethanedithioamide in 1:1, 1:2, and 2:2 mole proportions. The structures of these compounds have been elucidated from its physico-chemical and spectral data and by correlation with well-known products. Preliminary screening of these compounds for biological activity against several microorganisms has indicated that they are selective growth inhibitors of Mycobacterium tuberculosis in particular.

摘要

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