Rossini P M, Caltagirone C, Castriota-Scanderbeg A, Cicinelli P, Del Gratta C, Demartin M, Pizzella V, Traversa R, Romani G L
IRCCS Ospedale di Riabilitazione S. Lucia, Roma, Italy.
Neuroreport. 1998 Jun 22;9(9):2141-6. doi: 10.1097/00001756-199806220-00043.
The anatomical and functional correlates of the hand sensorimotor areas was investigated in a stroke patient with a malacic lesion in the left fronto-parieto-temporal cortex. The patient presented hemiplegia and motor aphasia 12 months earlier, followed by an excellent motor recovery. Transcranial magnetic stimulation mapping, functional magnetic resonance and magnetoencephalography were used as methods of functional imaging and all yielded consistent results. In particular, an asymmetrical enlargement and posterior shift of the sensorimotor areas localized in the affected hemisphere were found with all three techniques. Aspects related to brain 'plasticity' for functional recovery are discussed.
在一名左额颞顶叶皮质出现软化灶病变的中风患者中,对手部感觉运动区的解剖学和功能相关性进行了研究。该患者在12个月前出现偏瘫和运动性失语,随后运动功能得到了显著恢复。经颅磁刺激映射、功能磁共振成像和脑磁图被用作功能成像方法,所有这些方法都得出了一致的结果。特别是,通过这三种技术均发现,受影响半球的感觉运动区出现了不对称扩大和向后移位。文中还讨论了与功能恢复的大脑“可塑性”相关的问题。