Ioachim N J, McKenna P J, Delaney W E, Toth I, Chung F J
Arch Intern Med. 1978 Jul;138(7):1158-60.
A case of lymphocytic lymphoma of the small intestine was associated with cryoglobulinemia and amyloidosis. The neoplastic lymphoid cell demonstrated surface IgG membrane markers by immunofluorescence and immunoelectron microscopy. The cryoglobulins were characterized as monoclonal IgG3 proteins with lambda light chains. Amyloidosis of the small intestine and regional lymph nodes was found in association with lymphatic infiltration of these organs, suggesting the production of amyloid in situ.
一例小肠淋巴细胞性淋巴瘤与冷球蛋白血症及淀粉样变性相关。通过免疫荧光和免疫电子显微镜检查，肿瘤性淋巴细胞显示表面IgG膜标志物。冷球蛋白被鉴定为具有λ轻链的单克隆IgG3蛋白。在小肠和区域淋巴结的淀粉样变性中发现这些器官有淋巴浸润，提示淀粉样物质原位产生。
