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系统性轻链沉积病与淀粉样变性的关联:三例累及肾脏患者的报告

Association of systemic light-chain deposition disease and amyloidosis: a report of three patients with renal involvement.

作者信息

Jacquot C, Saint-Andre J P, Touchard G, Nochy D, D'Auzac de Lamartinie C, Oriol R, Druet P, Bariety J

出版信息

Clin Nephrol. 1985 Aug;24(2):93-8.

PMID:3930115
Abstract

Three patients with renal involvement, plasma cell dyscrasia and systemic light chain deposition are reported in whom well characterized amyloid deposits were also found in the vessel walls. This association, not yet reported, is probably more frequent than believed and still brings nearer these two manifestations of monoclonal light chain deposition. Whether or not the finding of amyloid deposits during systemic light chain deposition is a separate entity and modifies the prognosis remains to be answered.

摘要

报告了3例有肾脏受累、浆细胞异常增生症和系统性轻链沉积的患者,在其血管壁中也发现了特征明确的淀粉样沉积物。这种尚未见报道的关联可能比人们认为的更为常见,并且使这两种单克隆轻链沉积表现更紧密相关。系统性轻链沉积时淀粉样沉积物的发现是否为一个独立实体以及是否会改变预后仍有待解答。

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