Hauke R J, Greiner T C, Smir B N, Vose J M, Tarantolo S R, Bashir R M, Bierman P J
Department of Medicine, University of Nebraska Medical Center, Omaha 68198-8065, USA.
Bone Marrow Transplant. 1998 Jun;21(12):1271-4. doi: 10.1038/sj.bmt.1701258.
Epstein-Barr virus-associated lymphoproliferative disorders have been frequently reported as a complication of solid organ and allogeneic bone marrow transplantation. Their occurrence is rare after autologous bone marrow transplantation (BMT) with only five published reports in the literature. We report two cases of post-transplant lymphoproliferative disorder occurring after autologous BMT for Hodgkin's disease and non-Hodgkin's lymphoma. Post-transplant lymphoproliferative disorders can occur after autologous BMT and should be included in the differential diagnosis of patients with persistent fever, adenopathy or pulmonary infiltrates.
爱泼斯坦-巴尔病毒相关的淋巴增殖性疾病经常被报道为实体器官和异基因骨髓移植的一种并发症。自体骨髓移植(BMT)后其发生较为罕见,文献中仅有五篇已发表的报告。我们报告了两例自体BMT治疗霍奇金病和非霍奇金淋巴瘤后发生的移植后淋巴增殖性疾病。移植后淋巴增殖性疾病可发生于自体BMT后,对于持续发热、淋巴结肿大或肺部浸润的患者,应将其纳入鉴别诊断。