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含膳食纤维的肠内营养制剂对术后患者粪便参数的影响。

The effect of enteral fibre-containing feeds on stool parameters in the post-surgical period.

作者信息

Khalil L, Ho K H, Png D, Ong C L

机构信息

Dietetics Department, National University Hospital, Singapore.

出版信息

Singapore Med J. 1998 Apr;39(4):156-9.

PMID:9676145
Abstract

BACKGROUND/AIM OF STUDY: Specialised nutritional support includes both enteral and parenteral routes. When oral intake is not an option, but gastro-intestinal function is present, enteral tube feeding should be considered. However, one of the complications of enteral feeding access is diarrhoea. The aim of this study was to test the effect of fibre on a local population, in a prospective, single-blinded trial to determine whether the presence of fibre in enteral feeds reduced the incidence of diarrhoea in Asian patients.

METHODS

Sixteen post-surgical candidates were randomly assigned to receive a fibre-supplemented (FSF) enteral formula or a fibre-free formula (FFF) for 10 days post-surgery to assess the usefulness of FSF in reducing the incidence of diarrhoea in tube-fed patients. Differences in stool consistency, stool frequency, capillary blood glucose and serum albumin levels between the two groups were determined. Antibiotic usage in both groups was noted.

RESULTS

Patients in the FSF group had more bowel movements throughout the 10-day period and firmer stools than the FFF group, but this difference was not statistically significant (p = 0.39). There were no significant differences in daily mean glucose levels between both groups.

CONCLUSION

We conclude that there is insufficient evidence that fibre-containing enteral formulae reduce the incidence of diarrhoea in tube-fed patients in the short term. However, these products could inherently be included for patients on tube-feeds during extended periods, with the prospect of maintaining gut function integrity and flora.

摘要

研究背景/目的:特殊营养支持包括肠内和肠外途径。当无法经口摄入,但胃肠道功能存在时,应考虑肠内管饲。然而,肠内喂养通路的并发症之一是腹泻。本研究的目的是在一项前瞻性单盲试验中,测试纤维对当地人群的影响,以确定肠内营养制剂中纤维的存在是否能降低亚洲患者腹泻的发生率。

方法

16名外科手术候选患者被随机分配,在术后10天接受含纤维的肠内配方制剂(FSF)或无纤维配方制剂(FFF),以评估FSF在降低管饲患者腹泻发生率方面的有效性。测定两组患者的粪便稠度、排便频率、毛细血管血糖和血清白蛋白水平的差异。记录两组患者的抗生素使用情况。

结果

FSF组患者在整个10天期间的排便次数比FFF组多,粪便也更硬,但这种差异无统计学意义(p = 0.39)。两组患者的每日平均血糖水平无显著差异。

结论

我们得出结论,没有足够的证据表明含纤维的肠内配方制剂能在短期内降低管饲患者腹泻的发生率。然而,这些产品可以在长期管饲的患者中使用,有望维持肠道功能的完整性和菌群。

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