Morisi G, Chiodo F, Patriarca M, Menditto A
Laboratorio di Biochimica Clinica, Istituto Superiore di Sanità, Roma.
Ann Ist Super Sanita. 1998;34(1):17-26.
The biological surveys of the general population against the risk of lead intoxication carried out in Italy--in accomplishment both of the EEC directive EEC 77/312 and the Presidential Decree 496/1982--have been always conceived as multicentric activities. Therefore, starting from the first campaign carried out in 1979, strict quality control procedures have been adopted. In brief, each participant laboratory used internal quality control samples and took part in external quality assessment exercises. In addition, ten percent of the blood samples collected during the campaign were analyzed as blind duplicate by both participating laboratories and a reference laboratory. In this paper the quality control procedures adopted will be presented and discussed in detail together with the quality of results obtained in each campaign.
在意大利开展的针对铅中毒风险的普通人群生物学调查——既是为了落实欧洲经济共同体（EEC）第77/312号指令，也是为了执行第496/1982号总统令——一直被视为多中心活动。因此，从1979年开展的首次活动开始，就采用了严格的质量控制程序。简而言之，每个参与实验室都使用内部质量控制样本，并参加外部质量评估活动。此外，活动期间采集的血液样本中有10%由参与实验室和一个参考实验室作为盲样复本进行分析。本文将详细介绍和讨论所采用的质量控制程序以及每次活动所获结果的质量。
