Lysaker P H, Bell M D, Bryson G J, Kaplan E
Hamilton Center Inc., The Greene County Center, Linton, Indiana 47441-0553, USA.
J Nerv Ment Dis. 1998 Jul;186(7):432-6. doi: 10.1097/00005053-199807000-00008.
Research has linked impaired insight in schizophrenia to poorer medication compliance and treatment outcome. It is unclear, however, whether poorer interpersonal function is also associated with impaired insight. To examine this question, subjects with schizophrenia or schizoaffective disorder were classified as having unimpaired (N = 44) or impaired (N = 57) insight, and their scores on Heinrichs et al.'s Quality of Life (QOL) Scale were compared. Multiple regressions were conducted to determine the relationship between individual components and social function. Results indicate that subjects with impaired insight had significantly poorer QOL interpersonal relation and intrapsychic foundation scores than unimpaired subjects, despite having equivalent deficit symptoms. Unawareness of the social consequences of illness was found to be the component of insight more closely linked to social dysfunction. This suggests that impairments in insight may be uniquely associated with social dysfunction.
研究表明，精神分裂症患者洞察力受损与较差的药物依从性及治疗效果相关。然而，人际功能较差是否也与洞察力受损有关尚不清楚。为探究这个问题，将精神分裂症或分裂情感性障碍患者分为洞察力未受损组（N = 44）和受损组（N = 57），并比较他们在海因里希斯等人的生活质量（QOL）量表上的得分。进行多元回归以确定各个组成部分与社会功能之间的关系。结果表明，尽管洞察力受损组和未受损组的缺陷症状相当，但洞察力受损组在QOL人际关系和心理内在基础得分方面显著低于未受损组。研究发现，对疾病社会后果的无知是洞察力中与社会功能障碍联系更为紧密的组成部分。这表明洞察力受损可能与社会功能障碍存在独特关联。
