Senger M, Flores T, Glatting K, Ernst P, Hotz-Wagenblatt A, Suhai S
DKFZ - German Cancer Research Center, Department of Molecular Biophysics, Im Neuenheimer Feld 280, D-69120 Heidelberg, Germany.
Bioinformatics. 1998 Jun;14(5):452-7. doi: 10.1093/bioinformatics/14.5.452.
The user-friendly, graphical X-windows interface (WPI) to the GCG sequence analysis package can often not be used due to the lack of an X-server on PC or Macintosh computers. Because Web browsers like Netscape are much more common on those platforms, we decided to develop W2H, a WWW interface to the GCG Sequence Analysis Software Package with nearly the same functionality as the X-windows interface WPI.
The new WWW interface (W2H) to the GCG Sequence Analysis Software Package (Wisconsin Package) supports modern Web technologies, like client-pull method, or embedded scripting language, and provides a reasonable platform independence. The interface is quite comprehensive with advanced features like sequence selector, search set builder, enzyme chooser, access to sequence databases, uploading client files to the GCG server or displaying and manipulating graphical outputs in addition to GCG analysis programs. W2H also manages secure access to both GCG server and user data. For special environments, like workshops, conferences and company intranets, there is a special mode (Intranet mode) with less security constraints. The behaviour of W2H is mostly controlled by meta-data files describing the applications and giving a base for dynamic creation of HTML documents. This paper presents mainly the development approaches used, and architectural design aspects of W2H.
W2H is available by ftp://ftp.ebi.ac. uk/pub/software/unix/w2h or ftp://genome.dkfz-heidelberg.de/pub/w2h
由于个人电脑或苹果机上缺少X服务器，通常无法使用面向GCG序列分析软件包的用户友好型图形X窗口界面（WPI）。鉴于诸如Netscape之类的网络浏览器在这些平台上更为常见，我们决定开发W2H，即一个面向GCG序列分析软件包的万维网界面，其功能与X窗口界面WPI几乎相同。
面向GCG序列分析软件包（威斯康星软件包）的新万维网界面（W2H）支持现代网络技术，如客户端拉取方法或嵌入式脚本语言，并提供了合理的平台独立性。该界面相当全面，除了GCG分析程序外，还具备诸如序列选择器、搜索集构建器、酶选择器、访问序列数据库、将客户端文件上传到GCG服务器或显示和操作图形输出等高级功能。W2H还管理对GCG服务器和用户数据的安全访问。对于特殊环境，如研讨会、会议和公司内部网，有一种安全限制较少的特殊模式（内部网模式）。W2H的行为主要由描述应用程序并为动态创建HTML文档提供基础的元数据文件控制。本文主要介绍了所采用的开发方法以及W2H的架构设计方面。
可通过ftp://ftp.ebi.ac.uk/pub/software/unix/w2h或ftp://genome.dkfz - heidelberg.de/pub/w2h获取W2H。
