Adak T, Sharma V P, Orlov V S
Malaria Research Centre (ICMR), Sham Nath Marg, Delhi, India.
Am J Trop Med Hyg. 1998 Jul;59(1):175-9. doi: 10.4269/ajtmh.1998.59.175.
A five-year epidemiologic study of patients attending a malaria clinic in Delhi was conducted to find the relapse rate of infections with Plasmodium vivax, its seasonal correlation between the primary infection and subsequent relapses, the duration of the incubation period, and the patterns of relapse. By our definition, the relapse rate ranged from 23% to 44% depending on the duration of follow-up. The relapse pattern observed in the study clearly suggests the existence of both tropical and temperate zone types of P. vivax in the population characterized by distinct incubation periods and the possible existence of P. vivax subpopulations characterized by primary long incubation periods. The implication of different incubating forms of P. vivax on the epidemiology and control of malaria is also discussed.
在德里一家疟疾诊所对患者进行了一项为期五年的流行病学研究，以确定间日疟原虫感染的复发率、初次感染与后续复发之间的季节相关性、潜伏期的持续时间以及复发模式。根据我们的定义，复发率在23%至44%之间，具体取决于随访时间。该研究中观察到的复发模式清楚地表明，在该人群中存在潜伏期不同的热带和温带类型的间日疟原虫，并且可能存在以初次长潜伏期为特征的间日疟原虫子种群。还讨论了间日疟原虫不同潜伏形式对疟疾流行病学和控制的影响。
