Murri L, Gori S, Massetani R, Bonanni E, Marcella F, Milani S
Department of Neuroscience, University of Pisa, Italy.
Neurophysiol Clin. 1998 Jun;28(3):249-57. doi: 10.1016/S0987-7053(98)80115-9.
The sensitivity of quantitative electroencephalogram (EEG) was compared with that of conventional EEG in patients with acute ischaemic stroke. In addition, a correlation between quantitative EEG data and computerized tomography (CT) scan findings was carried out for all the areas of lesion in order to reassess the actual role of EEG in the evaluation of stroke. Sixty-five patients were tested with conventional and quantitative EEG within 24 h from the onset of neurological symptoms, whereas CT scan was performed within 4 days from the onset of stroke. EEG was recorded from 19 electrodes placed upon the scalp according to the International 10-20 System. Spectral analysis was carried out on 30 artefact-free 4-sec epochs. For each channel absolute and relative power were calculated for the delta, theta, alpha and beta frequency bands and such data were successively represented in colour-coded maps. Ten patients with extensive lesions documented by CT scan were excluded. The results indicated that conventional EEG revealed abnormalities in 40 of 55 cases, while EEG mapping showed abnormalities in 46 of 55 cases: it showed focal abnormalities in five cases and nonfocal abnormalities in one of six cases which had appeared to be normal according to visual inspection of EEG. In a further 11 cases, where the conventional EEG revealed abnormalities in one hemisphere, the quantitative EEG and maps allowed to further localize abnormal activity in a more localized way. The sensitivity of both methods was higher for frontocentral, temporal and parieto-occipital cortical-subcortical infarctions than for basal ganglia and internal capsule lesions; however, quantitative EEG was more efficient for all areas of lesion in detecting cases that had appeared normal by visual inspection and was clearly superior in revealing focal abnormalities. When we considered the electrode related to which the maximum power of the delta frequency band is recorded, a fairly close correlation was found between the localization of the maximum delta power and the position of lesions documented by CT scan for all areas of lesion excepting those located in the striatocapsular area.
在急性缺血性中风患者中，对定量脑电图（EEG）与传统EEG的敏感性进行了比较。此外，针对所有病变区域，对定量EEG数据与计算机断层扫描（CT）扫描结果进行了相关性分析，以重新评估EEG在中风评估中的实际作用。65例患者在出现神经症状后的24小时内接受了传统EEG和定量EEG检测，而CT扫描在中风发作后的4天内进行。根据国际10-20系统，在头皮上放置19个电极记录EEG。对30个无伪迹的4秒时段进行频谱分析。对于每个通道，计算δ、θ、α和β频段的绝对功率和相对功率，并将这些数据依次以彩色编码图表示。10例经CT扫描证实有广泛病变的患者被排除。结果表明，传统EEG在55例中有40例显示异常，而EEG图谱在55例中有46例显示异常：在6例经EEG目视检查看似正常的病例中，有5例显示局灶性异常，1例显示非局灶性异常。在另外11例中，传统EEG显示一个半球有异常，定量EEG和图谱能够以更局部化的方式进一步定位异常活动。两种方法对额中央、颞叶和顶枕皮质-皮质下梗死的敏感性均高于基底节和内囊病变；然而，定量EEG在检测目视检查看似正常的病例时，对所有病变区域更有效，在揭示局灶性异常方面明显更具优势。当我们考虑记录δ频段最大功率的电极时，除位于纹状囊区的病变外，在所有病变区域，δ最大功率的定位与CT扫描记录的病变位置之间发现了相当密切的相关性。
