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对一种新的视野阈值策略——瑞典交互阈值算法(SITA)在显性和可疑青光眼患者中的评估。

Evaluation of a new perimetric threshold strategy, SITA, in patients with manifest and suspect glaucoma.

作者信息

Bengtsson B, Heijl A

机构信息

Department of Ophthalmology, Malmö University Hospital, Sweden.

出版信息

Acta Ophthalmol Scand. 1998 Jun;76(3):268-72. doi: 10.1034/j.1600-0420.1998.760303.x.

DOI:10.1034/j.1600-0420.1998.760303.x
PMID:9686835
Abstract

PURPOSE

To evaluate the performance of the new perimetric threshold strategy SITA relative to older methods.

METHOD

Thirty-two patients with either glaucoma or ocular hypertension performed two threshold visual field tests with each of three threshold strategies, SITA, Humphrey Full Threshold, and Fastpac. Testing was distributed over three visits, and testing order was balanced between strategies to control for order effects.

RESULTS

SITA tests consumed 54% of the time taken by Full Threshold tests on average, and 85% of Fastpac tests; SITA's test times were significantly shorter than those of Full Threshold (p<0.0001) and Fastpac (p=0.0008). Test-retest threshold variability did not differ significantly between strategies. Intertest variability of the pattern deviation analysis was lowest in SITA (p<0.01) relative to both Full Threshold and Fastpac. Both SITA and Fastpac showed higher than expected average sensitivities relative to Full Threshold. SITA and Fastpac showed approximately the same amount of visual field loss. There was a significant relationship between Mean Deviation and the SITA function used to shorten stimulus sequences at points where measurement errors are small (p<0.0001).

CONCLUSION

Our results suggest that SITA matches the precision of older thresholding methods, consuming considerably and significantly less test time. This indicates that SITA could replace Full Threshold as the standard clinical test used in glaucoma management, without decreasing the quality of test results.

摘要

目的

评估新的视野阈值策略瑞典交互阈值算法(SITA)相对于旧方法的性能。

方法

32例青光眼或高眼压症患者分别采用三种阈值策略(SITA、Humphrey全阈值和快速阈值程序Fastpac)进行两次阈值视野测试。测试分三次就诊进行,测试顺序在各策略间保持平衡,以控制顺序效应。

结果

SITA测试平均耗时为全阈值测试的54%,快速阈值程序测试的85%;SITA的测试时间显著短于全阈值测试(p<0.0001)和快速阈值程序测试(p=0.0008)。各策略间重测阈值变异性无显著差异。模式偏差分析的测试间变异性在SITA中最低(p<0.01),相对于全阈值和快速阈值程序均是如此。相对于全阈值,SITA和快速阈值程序均显示出高于预期的平均敏感度。SITA和快速阈值程序显示出大致相同程度的视野缺损。平均偏差与用于在测量误差较小的点缩短刺激序列的SITA函数之间存在显著相关性(p<0.0001)。

结论

我们的结果表明,SITA与旧的阈值方法精度相当,测试时间大幅显著缩短。这表明SITA可取代全阈值作为青光眼管理中的标准临床测试,而不降低测试结果质量。

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