Schönau E
University Children's Hospital Cologne, Germany.
Pediatr Nephrol. 1998 Jun;12(5):420-9. doi: 10.1007/s004670050479.
The monitoring of bone metabolism and skeletal development during childhood and adolescence is becoming increasingly important in the prevention of osteoporosis. This is especially important in patients with chronic disorders. The predominant changes in the skeletal system during growth occur as geometric adaptation processes which lead to an increase in bone mass and bone strength. These changes can be measured with linear absorption methods (single-photon absorptiometry, dual-photon absorptiometry, dual-energy X-ray absorptiometry), computed tomographic procedures (peripheral quantitative computed tomography, quantitative computed tomography), and sonographic procedures. The aim of this review is to explain the problems of interpretation of the investigations due to growth-dependent changes. Almost all methods and their parameters, such as bone density, spongiosa density, cortical density, ultrasound transmission velocity, etc., are influenced, in varying degree, by growth-dependent skeletal changes.
在儿童和青少年时期监测骨代谢和骨骼发育对于预防骨质疏松症变得越来越重要。这在患有慢性疾病的患者中尤为重要。生长过程中骨骼系统的主要变化是作为几何适应过程发生的，这会导致骨量和骨强度增加。这些变化可以用线性吸收法（单光子吸收法、双光子吸收法、双能X线吸收法）、计算机断层扫描程序（外周定量计算机断层扫描、定量计算机断层扫描）和超声检查程序来测量。这篇综述的目的是解释由于生长相关变化导致的检查结果解释问题。几乎所有方法及其参数，如骨密度、松质骨密度、皮质骨密度、超声传播速度等，都在不同程度上受到生长相关骨骼变化的影响。
