白塞病与人类白细胞抗原系统。
Behçet disease and the HLA system.
作者信息
Takano M, Miyajima T, Kiuchi M, Ohmori K, Amemiya H
出版信息
Tissue Antigens. 1976 Aug;8(2):95-9.
PMID:968901
Abstract
Seventy-three unrelated patients with Behçet disease together with 33 members of seven families with at least two patients per family were tissue typed for 26 antigens of the HLA system. The patients with the complete type of Behçet disease were found to have HLA-B5 more significantly than healthy individuals. Family studies suggest that the genes closely linked to HLA locus influence the degree of severity of Behçet disease.
摘要
对73例无血缘关系的白塞病患者以及7个家庭的33名成员（每个家庭至少有两名患者）进行了HLA系统26种抗原的组织分型。发现完全型白塞病患者的HLA - B5比健康个体更为显著。家族研究表明，与HLA基因座紧密连锁的基因影响白塞病的严重程度。
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