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[胸腔积液]

[Pleural effusion].

作者信息

Thomas P, Castelnau O, Kleisbauer J P

机构信息

Département des maladies respiratoires, Hôpital ste-Marguerite, Marseille.

出版信息

Rev Mal Respir. 1998 Jun;15(3 Pt 2):363-7.

PMID:9690306
Abstract

Bronchial cancer associated with a homolateral malignant pleurisy is classed as T4 whether the pleural disease is a direct extension or metastatic. Effusions without neoplastic cells do not enter into the TNM classification. Investigations of pleural disease consist initially of needle biopsies, completed sometimes by a thoracoscopy, which enable a precise staging and also the achievement of a pleurodesis. A review of the literature does not currently establish the value of a pleurectomy in cases of a homolateral effusion in bronchial carcinoma. Surgical excision may be carried out in a case of neoplastic pleurisy where no pleural invasion is found without knowing the benefits in terms of survival. The inverse exists, with local or diffuse pleural invasion without pleurisy, which are difficult to evaluate by imagery techniques. Thus certain authors recommend pleural lavage during surgical operations for bronchial cancer even without pleural disease: positive cytology seems to be a poor prognostic feature and would justify adjuvant treatment. Thoracoscopy should be carried out when the neoplastic nature of a pleurisy has not been established by needle biopsy in order to evaluate the resectability of the tumour in the absence of surgical contra-indication. In the case of a disabling neoplastic pleurisy a pleurodesis carried out at the time of pleuroscopy may avoid the recurrence of the effusion. Talc is most often employed for pleurodesis but Bleomycin or Tetracycline are also used. In the case of failure to re-expand a shrunken lung the failure of the pleurodesis may lead to a pleuroperitoneal shunt. The type of homolateral pleural disease in bronchial cancer with local invasion by contiguity as against pleural metastases should appear in the TNM classification because there are different treatments and also a different prognosis.

摘要

伴有同侧恶性胸膜炎的支气管癌,无论胸膜病变是直接蔓延还是转移,均归类为T4。无肿瘤细胞的胸腔积液不纳入TNM分类。胸膜疾病的检查最初包括针吸活检,有时辅以胸腔镜检查,这有助于精确分期并实现胸膜固定术。目前文献综述尚未明确胸膜切除术在支气管癌同侧胸腔积液病例中的价值。在未发现胸膜侵犯的肿瘤性胸膜炎病例中,可进行手术切除,但尚不清楚其对生存的益处。反之,存在局部或弥漫性胸膜侵犯但无胸膜炎的情况,难以通过影像学技术评估。因此,某些作者建议即使在无胸膜疾病的支气管癌手术中也进行胸膜灌洗:阳性细胞学似乎是不良预后特征,可为辅助治疗提供依据。当针吸活检未确定胸膜炎的肿瘤性质时,应进行胸腔镜检查,以便在无手术禁忌证的情况下评估肿瘤的可切除性。对于导致功能障碍的肿瘤性胸膜炎,在胸腔镜检查时进行胸膜固定术可避免胸腔积液复发。滑石粉最常用于胸膜固定术,但也使用博来霉素或四环素。在肺萎陷无法复张的情况下,胸膜固定术失败可能导致胸膜腹膜分流。支气管癌同侧胸膜疾病中,局部连续性侵犯与胸膜转移的类型应纳入TNM分类,因为治疗方法不同,预后也不同。

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[Pleural effusion].[胸腔积液]
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