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埃塞俄比亚细叶没药树伤口诱导树皮渗出物的萜类成分

Terpenoid composition of the wound-induced bark exudate of Commiphora tenuis from Ethiopia.

作者信息

Asres K, Tei A, Moges G, Sporer F, Wink M

出版信息

Planta Med. 1998 Jun;64(5):473-5. doi: 10.1055/s-2006-957489.

Abstract

The bark of Commiphora tenuis Vollensen exudes a translucent, free-flowing odoriferous liquid upon wounding which was analysed by capillary GLC and GLC-MS. 42 mono- and sesquiterpenes were detected and 37 identified. The main components of the monoterpenoid fraction were alpha-pinene (60.8%), beta-pinene (8.8%), sabinene (6.3%), alpha-thujene (8.9%), limonene (5.5%), 3-carene (3.7%), beta-myrcene (1.8%), and beta-elemene (1.1%) constituting 97% of the oil. Identified sesquiterpenoid components constituted approximately 1.6% of the oil. Oleanolic acid acetate was isolated and identified as the main triterpene from the resin by 1H- and 13C-NMR. Three other triterpenes of the olean-12-ene group were also detected using GC-MS. The essential oil exhibited antibacterial activities against Staphylococcus aureus. Proteus mirabilis and E. coli with MIC between 0.5 and 1%.

摘要

细叶没药树(Commiphora tenuis Vollensen)的树皮在受伤时会渗出一种半透明、可自由流动的有气味液体,对此采用毛细管气相色谱法和气相色谱-质谱联用法进行了分析。检测到42种单萜和倍半萜,并鉴定出37种。单萜类成分的主要成分是α-蒎烯(60.8%)、β-蒎烯(8.8%)、桧烯(6.3%)、α-侧柏烯(8.9%)、柠檬烯(5.5%)、3-蒈烯(3.7%)、β-月桂烯(1.8%)和β-榄香烯(1.1%),占精油的97%。鉴定出的倍半萜类成分约占精油的1.6%。通过1H-和13C-NMR从树脂中分离并鉴定出齐墩果酸乙酸酯为主要三萜。还使用气相色谱-质谱联用仪检测到了齐墩果-12-烯类的其他三种三萜。该精油对金黄色葡萄球菌、奇异变形杆菌和大肠杆菌具有抗菌活性,最低抑菌浓度在0.5%至1%之间。

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