Liu Kai, Rossi Paul-Georges, Ferrari Bernard, Berti Liliane, Casanova Joseph, Tomi Félix
Université de Corse, UMR CNRS 6134 SPE, Equipe Chimie et Biomasse, Route des Sanguinaires, 20000 Ajaccio, France.
Phytochemistry. 2007 Jun;68(12):1698-705. doi: 10.1016/j.phytochem.2007.04.027. Epub 2007 Jun 4.
A detailed analysis of Santolina corsica essential oil was carried out by combination of GC (RI), GC-MS and 13C NMR spectroscopy. After fractionation by column chromatography, 50 components were identified, accounting for 88.2% of the total amount of the oil. The chemical composition was dominated by monoterpene hydrocarbons, myrcene (34.6%), santolina triene (13.5%) and beta-phellandrene (11.7%). Beside the main compounds, we noted the occurrence of irregular mono and sesquiterpenes belonging to five families: santolinane, artemisane, chrysanthemane, lavandulane and sesquilavandulane. Three compounds, lyratyl butyrate, isolyratone and epi-isolyratol were isolated and their structure elucidated by 2D NMR. Antibacterial activity was tested against six bacteria strains. The essential oil was effective against Staphylococcus aureus and C. jejuni. Lyratol was identified as main responsive of the antibacterial activity. The content of lyratol was measured in 33 oil samples isolated from individual plants.
通过气相色谱（保留指数）、气相色谱 - 质谱联用和碳 - 13核磁共振光谱相结合的方法，对科西嘉神圣亚麻精油进行了详细分析。经柱色谱分离后，鉴定出50种成分，占精油总量的88.2%。其化学成分以单萜烃类为主，月桂烯（34.6%）、神圣亚麻三烯（13.5%）和β-水芹烯（11.7%）。除了主要化合物外，我们还注意到存在属于五个家族的不规则单萜和倍半萜：神圣亚麻烷、青蒿烷、菊烷、薰衣草烷和倍半薰衣草烷。分离出了三种化合物，丁酸赖百当酯、异赖百当酮和表异赖百当醇，并通过二维核磁共振确定了它们的结构。对六种细菌菌株进行了抗菌活性测试。该精油对金黄色葡萄球菌和空肠弯曲菌有效。赖百当醇被确定为抗菌活性的主要响应成分。测定了从单株植物中分离出的33个油样中赖百当醇的含量。
