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髋部骨折患病率的长期趋势:髋部骨折发病率和生存率的影响

Long-term trends in hip fracture prevalence: the influence of hip fracture incidence and survival.

作者信息

Melton L J, Therneau T M, Larson D R

机构信息

Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA.

出版信息

Osteoporos Int. 1998;8(1):68-74. doi: 10.1007/s001980050050.

Abstract

In this population-based descriptive study covering the 65-year period, 1928-92, there was a 5-fold increase in hip fracture prevalence among Rochester, Minnesota residents between 1928-42 and 1973-82, from 135.8 to 675.8 per 100,000. This change was dictated almost entirely by an increase in the incidence of first hip fractures due to moderate trauma (n = 2058) that was observed among Rochester women through 1950, and among men through 1980, that affected all age groups. Declining incidence rates thereafter led to a 9% fall in hip fracture prevalence from 1973-82 to 1983-92 to a rate of 612.7 per 100,000. A 13.7-year increase in age at first hip fracture over the study period was accounted for by aging of the underlying population, and a comparable 13.9-year increase in the age at death following hip fracture appeared to result from improved survival in the population generally. Thus, trends in hip fracture prevalence were mainly determined by changes in incidence rather than relative changes in age at onset and death following hip fracture.

摘要

在这项基于人群的描述性研究中,研究时段为1928年至1992年这65年,明尼苏达州罗切斯特市居民的髋部骨折患病率在1928 - 1942年至1973 - 1982年间增长了5倍,从每10万人135.8例增至675.8例。这一变化几乎完全是由中度创伤导致的首次髋部骨折发病率上升所致(n = 2058),在1950年前的罗切斯特女性以及1980年前的男性中观察到这种情况,且涉及所有年龄组。此后发病率下降导致髋部骨折患病率从1973 - 1982年到1983 - 1992年下降了9%,降至每10万人612.7例。在研究期间,首次髋部骨折年龄增加了13.7岁是由于基础人群老龄化,而髋部骨折后死亡年龄有类似的13.9岁增加似乎是由于总体人群生存率提高。因此,髋部骨折患病率的趋势主要由发病率变化决定,而非髋部骨折发病和死亡年龄的相对变化。

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