Division of Epidemiology, Department of Health Sciences Research, College of Medicine, Mayo Clinic, Rochester, MN 55905, USA.
Osteoporos Int. 2009 May;20(5):687-94. doi: 10.1007/s00198-008-0742-8. Epub 2008 Sep 17.
The decline in hip fracture incidence is now accompanied by a further reduction in the likelihood of a recurrent hip fracture among survivors of the first fracture.
Hip fracture incidence is declining in North America, but trends in hip fracture recurrence have not been described.
All hip fracture events among Olmsted County, Minnesota residents in 1980-2006 were identified. Secular trends were assessed using Poisson regression, and predictors of recurrence were evaluated with Andersen-Gill time-to-fracture regression models.
Altogether, 2,752 hip fractures (median age, 83 years; 76% female) were observed, including 311 recurrences. Between 1980 and 2006, the incidence of a first-ever hip fracture declined by 1.37%/year for women (p < 0.001) and 0.06%/year for men (p = 0.917). Among 2,434 residents with a first-ever hip fracture, the cumulative incidence of a second hip fracture after 10 years was 11% in women and 6% in men with death treated as a competing risk. Age and calendar year of fracture were independently associated with hip fracture recurrence. Accounting for the reduction in first-ever hip fracture rates over time, hip fracture recurrence appeared to decline after 1997.
A recent reduction in hip fracture recurrence is somewhat greater than expected from the declining incidence of hip fractures generally. Additional research is needed to determine the extent to which this can be attributed to improved patient management.
髋部骨折发生率的下降现在伴随着首次骨折存活者再次发生髋部骨折的可能性进一步降低。
北美的髋部骨折发生率正在下降,但髋部骨折复发的趋势尚未描述。
在 1980-2006 年,明尼苏达州奥姆斯特德县的所有髋部骨折事件均被确定。使用泊松回归评估时间趋势,并用安德森-吉尔骨折时间回归模型评估复发的预测因素。
共观察到 2752 例髋部骨折(中位数年龄 83 岁;76%为女性),其中 311 例复发。1980 年至 2006 年间,女性首次髋部骨折的发生率每年下降 1.37%(p<0.001),男性每年下降 0.06%(p=0.917)。在 2434 例首次髋部骨折的居民中,女性 10 年后再次发生髋部骨折的累积发生率为 11%,男性为 6%,死亡被视为竞争风险。年龄和骨折年份与髋部骨折复发独立相关。考虑到首次髋部骨折发生率随时间的降低,髋部骨折复发似乎在 1997 年后有所下降。
髋部骨折复发的近期减少略高于总体髋部骨折发生率的下降。需要进一步研究以确定在多大程度上可以归因于患者管理的改善。