Vasil'eva E N
Vopr Pitan. 1976 May-Jun(1):6-11.
The influence exerted by the quality of alimentary protein on the composition of the secreted bile, morphology of the liver and gallbladder, as well as on the formation of gallstones was studied in experiments with rats and hamsters. It is shown that with inclusion in an experimental fat-free ration of qualitatively incomplete protein gelatin (instead of caseine) the frequency of the gallstones formation increases by almost 6 times. In animals this is attended by a reduced concentration of a number of major bile components. Upon feeding for 2 weeks on lithogenic ration with gelatin morphological investigations disclose inflammatory changes in the gallbladder wall, and after a lapse of 3 weeks--multiple exulcerations in the mucosa and a dense gross sediment in the gallbladder lumen.
在大鼠和仓鼠实验中，研究了食物蛋白质质量对分泌胆汁的成分、肝脏和胆囊形态以及胆结石形成的影响。结果表明，在实验性无脂日粮中加入质量不完全的蛋白质明胶（代替酪蛋白），胆结石形成的频率几乎增加了6倍。在动物中，这伴随着一些主要胆汁成分浓度的降低。用含明胶的致石日粮喂养2周后，形态学研究发现胆囊壁有炎症变化，3周后，黏膜出现多处溃疡，胆囊腔内有致密的肉眼可见沉积物。
