Beckman L, Sikström C, Mikelsaar A V, Krumina A, Ambrasiene D, Kucinskas V, Beckman G
Department of Medical Genetics, Umeå University, Sweden.
Hum Hered. 1998 Jul-Aug;48(4):185-91. doi: 10.1159/000022800.
Transferrin (TF) types were examined by isoelectric focusing in an attempt to elucidate migrations and admixture between populations in the Baltic Sea region. A highly significant heterogeneity between populations was found with respect to TFC subtypes as well as the rare TF variants B2, B0-1 and DCHI. With the exception for Estonia, increased frequencies of the TFC3 allele were observed east of the Baltic Sea. The island of Gotland in the middle of the Baltic Sea also showed a high TFC3 frequency indicating an eastern influence. The TFDCHI allele, a marker of eastern (Finno-Ugric) influence, was found in Finland and Estonia and on the island of Gotland, but not in mainland Sweden and in the Baltic peoples (Latvians and Lithuanians). These results indicate the presence of a Finno-Ugric, most likely Estonian or Livonian, genetic influence in the Gotland population.
通过等电聚焦对转铁蛋白（TF）类型进行了检测，旨在阐明波罗的海地区不同人群之间的迁移和混合情况。在TFC亚型以及罕见的TF变体B2、B0 - 1和DCHI方面，发现不同人群之间存在高度显著的异质性。除爱沙尼亚外，在波罗的海以东观察到TFC3等位基因频率增加。位于波罗的海中部的哥特兰岛也显示出较高的TFC3频率，表明受到东部的影响。TFDCHI等位基因是东部（芬兰 - 乌戈尔语族）影响的一个标记，在芬兰、爱沙尼亚和哥特兰岛被发现，但在瑞典大陆和波罗的海民族（拉脱维亚人和立陶宛人）中未发现。这些结果表明哥特兰岛人群中存在芬兰 - 乌戈尔语族的遗传影响，很可能是爱沙尼亚或利沃尼亚人的影响。
