Davidson I, Hebert C N
Bull World Health Organ. 1978;56(1):123-7.
Although the three standards have similar agglutinating activities, it was found that the first International Standard had about half the complement-fixing activity of the second International Standard and the EEC standard. The complement-fixing activities of the latter two standards were similar. On the basis of these results, showing that the agglutination and complement-fixation tests measure different biological activities in anti-Brucella abortus sera, the WHO Expert Committee on Biological Standardization in 1976 assigned separate unitages of agglutinating and complement-fixing activity to the second International Standard for Anti-Brucella abortus Serum.
尽管这三种标准品具有相似的凝集活性，但发现第一国际标准品的补体结合活性约为第二国际标准品和欧共体标准品的一半。后两种标准品的补体结合活性相似。基于这些结果表明凝集试验和补体结合试验检测的是抗流产布鲁氏菌血清中的不同生物学活性，1976年世界卫生组织生物标准化专家委员会为抗流产布鲁氏菌血清第二国际标准品分别指定了凝集活性单位和补体结合活性单位。
