Dickman C A, Sonntag V K
Division of Neurological Surgery, Barrow Neurological Institute, Mercy Healthcare Arizona, Phoenix 85013-4496, USA.
Neurosurgery. 1998 Aug;43(2):275-80; discussion 280-1. doi: 10.1097/00006123-199808000-00056.
To assess the outcomes associated with C1-C2 transarticular screw fixation.
The clinical outcomes of 121 patients treated with posterior C1-C2 transarticular screws and wired posterior C1-C2 autologous bone struts were evaluated prospectively. Atlantoaxial instability was caused by rheumatoid arthritis in 48 patients, C1 or C2 fractures in 45, transverse ligament disruption in 11, os odontoideum in 9, tumors in 6, and infection in 2.
Altogether, 226 screws were placed under lateral fluoroscopic guidance. Bilateral C1-C2 screws were placed in 105 patients; each of 16 patients had only one screw placed because of an anomalous vertebral artery (n = 13) or other pathological abnormality. Postoperatively, each patient underwent radiography and computed tomography to assess the position of the screw and healing. Most screws (221 screws, 98%) were positioned satisfactorily. Five screws were malpositioned (2%), but none were associated with clinical sequelae. Four malpositioned screws were reoperated on (one was repositioned, and three were removed). No patients had neurological complications, strokes, or transient ischemic attacks. Long-term follow-up (mean, 22 mo) of 114 patients demonstrated a 98% fusion rate. Two nonunions (2%) required occipitocervical fixation. In comparison, our C1-C2 fixations with wires and autograft (n = 74) had an 86% union rate.
Rigidly fixating C1-C2 instability with transarticular screws was associated with a significantly higher fusion rate than that achieved using wired grafts alone. The risk of screw malpositioning and catastrophic vascular or neural injury is small and can be minimized by assessing the position of the foramen transversaria on preoperative computed tomographic scans and by using intraoperative fluoroscopy and frameless stereotaxy to guide the screw trajectory.
评估C1-C2经关节螺钉固定的相关结果。
对121例行后路C1-C2经关节螺钉固定及后路C1-C2自体骨支撑钢丝固定治疗的患者的临床结果进行前瞻性评估。寰枢椎不稳由类风湿关节炎引起的有48例,C1或C2骨折45例,横韧带断裂11例,齿突骨9例,肿瘤6例,感染2例。
总共在侧位透视引导下置入226枚螺钉。105例患者置入双侧C1-C2螺钉;16例患者因椎动脉异常(n = 13)或其他病理异常仅置入1枚螺钉。术后,每位患者均接受X线摄影和计算机断层扫描以评估螺钉位置及愈合情况。大多数螺钉(221枚,98%)位置满意。5枚螺钉位置不佳(2%),但均未导致临床后遗症。4枚位置不佳的螺钉再次手术处理(1枚重新定位,3枚取出)。无患者发生神经并发症、中风或短暂性脑缺血发作。114例患者的长期随访(平均22个月)显示融合率为98%。2例不愈合(2%)需要枕颈固定。相比之下,我们采用钢丝和自体骨移植行C1-C2固定(n = 74)的愈合率为86%。
与单独使用钢丝移植相比,经关节螺钉牢固固定C1-C2不稳的融合率显著更高。螺钉位置不佳及灾难性血管或神经损伤的风险较小,通过术前计算机断层扫描评估横突孔位置以及术中使用透视和无框架立体定向技术引导螺钉轨迹可将风险降至最低。