Dini M, Colafranceschi M
Department of Plastic Surgery, University of Florence, Italy.
Am J Dermatopathol. 1998 Aug;20(4):399-402. doi: 10.1097/00000372-199808000-00014.
We observed so-called idiopathic scrotal calcinosis in a 36-year-old man who was cured successfully by simple excision of the affected skin. Histologically, the nodular lesions consisted of calcified amorphous basophilic masses and small granules within the dermis. One rounded aggregate of calcified basophilic material showed a slight positivity on immunostaining for cytokeratin. Some intact epidermoid cysts were also present, suggesting that dystrophic calcification, and possibly inflammation and rupture of epidermoid cysts, may be the main pathogenetic mechanism of the disease in most reported cases. In our opinion, the term idiopathic should refer to the individual cases that are etiologically undefined rather than the whole category of scrotal calcinosis.
我们在一名36岁男性中观察到所谓的特发性阴囊钙化症，通过简单切除受累皮肤成功治愈。组织学上，结节性病变由真皮内钙化的无定形嗜碱性团块和小颗粒组成。一个圆形的钙化嗜碱性物质聚集体在细胞角蛋白免疫染色上呈轻微阳性。还存在一些完整的表皮样囊肿，提示营养不良性钙化，可能还有表皮样囊肿的炎症和破裂，可能是大多数报道病例中该病的主要发病机制。我们认为，“特发性”一词应指病因不明的个别病例，而非阴囊钙化症的整个类别。
