Geirnaerdt M J, Hogendoorn P C, Taminiau A H, Bloem J L
Department of Radiology, Leiden University Medical Center.
Radiologe. 1998 Jun;38(6):502-8. doi: 10.1007/s001170050385.
Malignant cartilaginous tumors (chondrosarcomas) are, with a relative frequency of 20%, the second most common malignant tumors of bone after osteosarcoma. The diagnosis of chondrosarcoma can usually be made confidently based on combination of clinical information, radiographs, Gd-enhanced MR imaging, and histologic examination of a biopsy sample. The combination of these parameters is important because accuracy of histologic diagnosis is adversely affected by unrepresentative sampling of these usually large tumors. The prognosis of patients with chondrosarcoma becomes poorer with more axial location, higher histologic grade, larger tumor size and inadequate resection. By careful analysis of radiographs and Gd-enhanced MR imaging the radiologist has the ability to improve the management of patients with chondrosarcoma.
恶性软骨肿瘤（软骨肉瘤）相对发病率为20%，是仅次于骨肉瘤的第二常见骨恶性肿瘤。软骨肉瘤的诊断通常可根据临床信息、X线片、钆增强磁共振成像以及活检样本的组织学检查结果综合判断而确定。这些参数的综合很重要，因为这些通常较大的肿瘤取样不具有代表性会对组织学诊断的准确性产生不利影响。软骨肉瘤患者的预后会因肿瘤位于更靠近身体中轴线的位置、组织学分级更高、肿瘤体积更大以及切除不充分而变差。通过仔细分析X线片和钆增强磁共振成像，放射科医生有能力改善软骨肉瘤患者的治疗。
