Kurakin E S
Sechenov Medical Academy, Moscow, Russia.
Zh Mikrobiol Epidemiol Immunobiol. 1998 May-Jun(3):31-5.
In this article the results of the study of regularities in the development of outbreak morbidity in shigellosis, caused by S.flexneri 2a, in hospitals are presented. The study was carried out with the use of the method of typing by the plasmid profile. The study showed the continuity of the epidemic process in the foci which appeared at intervals considerably exceeding the incubation period. The fact of the interhospital spread of S.flexneri 2a was established. The strain causing the disease was identified by the characteristic set of plasmids and their size. The possibility of reinfection of patients with S.flexneri 2a under hospital conditions was confirmed. The possibility of changes in the main transmission routes in the course of the spread of S.flexneri 2a infection in closed groups was pointed out.
本文介绍了在医院中由福氏2a志贺菌引起的志贺菌病暴发发病率发展规律的研究结果。该研究采用质粒图谱分型法进行。研究表明，发病间隔时间远超过潜伏期的疫源地中，流行过程具有连续性。已证实福氏2a志贺菌存在医院间传播的情况。通过质粒的特征组合及其大小确定了致病菌株。证实在医院环境下患者有再次感染福氏2a志贺菌的可能性。指出了福氏2a志贺菌感染在封闭人群中传播过程中主要传播途径发生变化的可能性。
