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一项针对绝经后女性的随机步行试验:10年后对身体活动和健康的影响

A randomized walking trial in postmenopausal women: effects on physical activity and health 10 years later.

作者信息

Pereira M A, Kriska A M, Day R D, Cauley J A, LaPorte R E, Kuller L H

机构信息

Division of Epidemiology, University of Minnesota, Minneapolis 55454, USA.

出版信息

Arch Intern Med. 1998;158(15):1695-701. doi: 10.1001/archinte.158.15.1695.

DOI:10.1001/archinte.158.15.1695
PMID:9701104
Abstract

BACKGROUND

It is important to determine if permanent lifestyle changes may result from physical activity interventions and whether health may be affected by these changes.

OBJECTIVE

To conduct a 10-year follow-up of physical activity and self-reported health status in participants of a randomized clinical trial of walking intervention.

METHODS

Of the original 229 volunteer postmenopausal women who participated in the original clinical trial, 196 (N = 96 intervention and 100 controls) completed the 10-year follow-up telephone interview. The interview protocol included questions on self-reported walking for exercise and purposes other than exercise, the Paffenbarger sport and exercise index, functional status, and various chronic diseases and conditions.

RESULTS

The median values for both usual walking for exercise and total walking were significantly higher for walkers compared with controls (for both, P = .01), with median differences of 706 and 420 kcal/wk, respectively. After excluding women who reported heart disease during the original trial, 2 women in the walking group (2%) and 11 women in the control group (12%) reported physician-diagnosed heart disease over the last 10 years (P = .07). There were also fewer hospitalizations, surgeries, and falls among women in the walking group, although these differences were not statistically significant (P>.05).

CONCLUSIONS

Although limited by self-report, this study may be the first to demonstrate long-term exercise compliance to a randomized control trial in older women and to suggest that health benefits may have ensued as a result of these increased activity levels.

摘要

背景

确定体力活动干预是否会导致永久性的生活方式改变以及这些改变是否会影响健康非常重要。

目的

对一项步行干预随机临床试验的参与者进行为期10年的体力活动和自我报告健康状况随访。

方法

在最初参与临床试验的229名绝经后志愿者女性中,196人(N = 96名干预组和100名对照组)完成了为期10年的随访电话访谈。访谈协议包括关于自我报告的锻炼性步行和非锻炼目的步行、帕芬巴格运动和锻炼指数、功能状态以及各种慢性疾病和状况的问题。

结果

与对照组相比,步行者的锻炼性日常步行和总步行的中位数均显著更高(两者P = 0.01),中位数差异分别为706和420千卡/周。在排除最初试验期间报告患有心脏病的女性后,步行组有2名女性(2%),对照组有11名女性(12%)在过去10年中报告患有医生诊断的心脏病(P = .07)。步行组女性的住院、手术和跌倒次数也较少,尽管这些差异无统计学意义(P>0.05)。

结论

尽管本研究受自我报告的限制,但它可能是首个证明老年女性对随机对照试验长期运动依从性的研究,并表明这些增加的活动水平可能带来了健康益处。

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