Tardiff K, Marzuk P M, Leon A C, Hirsch C S, Portera L, Hartwell N
Department of Psychiatry, Cornell University Medical College, New York, NY 10021, USA.
Ann Emerg Med. 1998 Aug;32(2):151-4. doi: 10.1016/s0196-0644(98)70130-1.
To determine the HIV seroprevalence rates in relation to the demographic characteristics of victims, cause of death, and toxicology findings in a sample of victims of violence and accidents who presented to emergency departments before death.
This descriptive survey of a complete 3-year sample of homicides and accidents was conducted in 5 boroughs of New York City (population 7,322,564). Persons 15 years of age and older injured by intentional violence or accidents (excluding drug overdoses, falls from short heights, and suicides) who presented to hospitals, died, and were sent to the medical examiner were included. Standard methods were used to test plasma and serum samples for HIV and cocaine or its metabolite. Chi2 Tests compared HIV seroprevalence across groups according to demographic characteristics and toxicology findings. Logistic regression analysis was done for those variables found to be significant with chi2 tests. All statistical tests were conducted with 2-tailed alpha levels of .05.
Among the 1,242 subjects in the sample, 90 (7.2%) had positive findings. Male patients (8%) had higher rates than female patients (3.4%). HIV rates were highest among patients 35 to 44 years of age (20.8%), followed by the 45- to 54-year age group (9.6%) and 25- to 34-year age group (8.1%). Victims of homicide (8.2%) and accidents other than motor vehicle crashes (10.5%) had higher rates than victims of motor vehicle crashes (4%). Patients with positive results for cocaine (16.3%) were more likely than those with negative result (5.8%) to be HIV positive. There were no statistically significant differences by race, except that no Asians were HIV positive. Logistic regression analysis found that only age and positive cocaine results, not sex and race, were related to increased risk of HIV infection.
We found the rate of HIV infection among victims of fatal trauma was significant, especially in those with evidence of cocaine use. The HIV infection rate approximates the high end of the range of HIV rates found in studies before 1990. It further emphasizes the need for use of universal precautions in the care of trauma patients.
确定在死前被送往急诊科的暴力和事故受害者样本中,与受害者人口统计学特征、死因及毒理学结果相关的HIV血清阳性率。
对纽约市5个行政区(人口7322564)3年期间所有的凶杀案和事故样本进行了描述性调查。纳入15岁及以上因故意暴力或事故(不包括药物过量、从低处坠落和自杀)受伤、被送往医院、死亡并被送至法医处的人员。采用标准方法检测血浆和血清样本中的HIV以及可卡因或其代谢物。卡方检验根据人口统计学特征和毒理学结果比较不同组的HIV血清阳性率。对卡方检验中发现有显著意义的变量进行逻辑回归分析。所有统计检验的双侧α水平均为0.05。
在样本中的1242名受试者中,90人(7.2%)检测结果呈阳性。男性患者(8%)的阳性率高于女性患者(3.4%)。HIV阳性率在35至44岁的患者中最高(20.8%),其次是45至54岁年龄组(9.6%)和25至34岁年龄组(8.1%)。凶杀案受害者(8.2%)和非机动车事故受害者(10.5%)的阳性率高于机动车事故受害者(4%)。可卡因检测结果呈阳性的患者(16.3%)比检测结果呈阴性的患者(5.8%)更有可能HIV呈阳性。除了没有亚洲人HIV呈阳性外,不同种族之间没有统计学上的显著差异。逻辑回归分析发现,只有年龄和可卡因检测结果呈阳性与HIV感染风险增加有关,而性别和种族无关。
我们发现致命创伤受害者中的HIV感染率很高,尤其是那些有可卡因使用证据的人。HIV感染率接近1990年以前研究中发现的HIV感染率范围的上限。这进一步强调了在创伤患者护理中使用普遍预防措施的必要性。