Klerman L V, Cliver S P, Goldenberg R L
Am J Public Health. 1998 Aug;88(8):1182-5. doi: 10.2105/ajph.88.8.1182.
The objective of this study was to determine whether the length of the interval between pregnancies was associated with either preterm birth or intrauterine growth retardation in a low-income, largely Black population.
The study population consisted of 4400 women who had received prenatal care in county clinics and had two consecutive singleton births between 1980 and 1990.
Interpregnancy intervals were positively associated with age and negatively associated with the trimester in which care was initiated in the second pregnancy. Whites had shorter intervals than non-Whites. The percentage of preterm births increased as the length of the interpregnancy interval decreased, but only for women who had not had a previous preterm birth. The association between interval and preterm birth was maintained when other factors associated with preterm birth were controlled. There was no significant relationship between intrauterine growth retardation and interpregnancy interval.
Women, particularly those who are poor and young, should be advised of the potential harm to their infants of short interpregnancy intervals.
本研究的目的是确定在低收入、主要为黑人的人群中，妊娠间隔时间的长短是否与早产或胎儿宫内生长受限有关。
研究人群包括4400名在县诊所接受产前护理且在1980年至1990年间有两次连续单胎分娩的妇女。
妊娠间隔与年龄呈正相关，与第二次妊娠开始护理的孕周呈负相关。白人的妊娠间隔比非白人短。早产百分比随着妊娠间隔时间的缩短而增加，但仅适用于既往没有早产的妇女。当控制与早产相关的其他因素时，妊娠间隔与早产之间的关联依然存在。胎儿宫内生长受限与妊娠间隔之间没有显著关系。
应告知妇女，尤其是贫困和年轻妇女，妊娠间隔时间短对其婴儿可能存在危害。
