Siddiqui A R, Luby S P
Department of Community Health Sciences, Aga Khan University Hospital, Karachi, Pakistan.
Infect Control Hosp Epidemiol. 1998 Jul;19(7):526-9. doi: 10.1086/647865.
To confirm the presence of an outbreak of postoperative infections following laminectomy and to determine the infection rate after interventions were instituted.
Retrospective cohort study. Medical records were reviewed, personnel interviewed, and premises examined.
Surgical unit of hospital A in Pakistan.
Patients who had surgical laminectomy between January 1993 and July 1994.
Instructive program for nursing and medical staff in December 1993.
From January to December 1993, 6 (15%) of 41 laminectomy patients developed postoperative discitis. The risk of discitis varied significantly by surgeon (P = .016); patients who had one particular surgeon, surgeon A, were nine times more likely to develop postoperative infections than patients who did not have surgeon A. Patients were not consistently cleaned or shaved before coming to the operating room, and personnel moved back and forth between the operation theater and other parts of the hospital without changing their gowns or slippers. After the instructional intervention, between January and July 1994, 2 (6%) of 31 laminectomy patients developed postoperative discitis, a rate not significantly lower than in the preceding 12 months (P = .45). Overall, from January 1993 through July 1994, female patients were more likely to develop discitis than males (31% vs 7%; relative risk, 4.4; 95% confidence interval, 1.3-15.6; P < .032).
Endemic conditions require that laminectomy at hospital A be limited to those situations where the benefits of the surgery exceed the considerable risk of postoperative discitis.
确认椎板切除术后手术部位感染暴发的情况,并确定采取干预措施后的感染率。
回顾性队列研究。查阅病历、访谈工作人员并检查场所。
巴基斯坦A医院的外科病房。
1993年1月至1994年7月期间接受椎板切除术的患者。
1993年12月为护理和医务人员开展指导计划。
1993年1月至12月,41例椎板切除术患者中有6例(15%)发生术后椎间盘炎。不同外科医生的椎间盘炎发病风险差异显著(P = 0.016);由某一位特定外科医生A操刀的患者发生术后感染的可能性是未由该医生操刀患者的9倍。患者在进入手术室前未得到持续清洁或备皮,工作人员在手术室和医院其他区域之间来回穿梭,且不更换手术服或拖鞋。指导干预措施实施后,1994年1月至7月,31例椎板切除术患者中有2例(6%)发生术后椎间盘炎,该感染率与前12个月相比无显著降低(P = 0.45)。总体而言,1993年1月至1994年7月,女性患者发生椎间盘炎的可能性高于男性(31%对7%;相对风险为4.4;95%置信区间为1.3 - 15.6;P < 0.032)。
由于存在地方病流行情况,A医院的椎板切除术应仅限于手术益处超过术后椎间盘炎相当大风险的情况。