Daxer A, Blumthaler M, Schreder J, Ettl A
Abteilungen für Augenheilkunde, Landeshauptstadt St. Pölten, Austria.
Ophthalmic Res. 1998;30(5):286-90. doi: 10.1159/000055486.
To test the effectiveness of commercially available ultraviolet (UV)-protective eye drops (8-hydroxy-1-methylchinolinium methylsulphate) which are recommended for protection against both solar and artificial UV radiation.
The spectral transmission in the wavelength range from 250 to 500 nm was investigated in 1-nm steps using a high-resolution double monochromator with holographic gratings of 2,400 lines/mm and a 1,000-watt halogen lamp as light source. The transmission spectrum was measured for different values of the layer thickness.
The transmission of a liquid layer of about 10 microns, which corresponds to the thickness of the human tear film, shows a cut-off at 290 nm with a transmission of about 25-50% at shorter wavelengths. For wavelengths longer than 290 nm the transmission is higher than 90%. The threshold time ratio for keratitis formation with and without eye drops is above 0.93 considering solar radiation on the earth's surface and above 0.65 considering radiation from arc-welding, respectively.
The transmission spectrum of the eye drops under realistic conditions does not show a protective effect against solar UV radiation. However, there exists reduction of UVC radiation in the spectral range typical of artificial UV sources such as arc-welding. We cannot recommend the application of these eye drops as an UV-protective aid against eye damage by solar UV radiation.
测试市售的紫外线防护眼药水（8-羟基-1-甲基喹啉甲基硫酸盐）的有效性，该眼药水推荐用于防护太阳紫外线和人工紫外线辐射。
使用带有2400线/毫米全息光栅的高分辨率双单色仪和1000瓦卤钨灯作为光源，以1纳米的步长研究250至500纳米波长范围内的光谱透射率。针对不同的层厚度值测量透射光谱。
约10微米厚的液层（相当于人泪膜的厚度）的透射率在290纳米处截止，在较短波长下透射率约为25%至50%。对于波长大于290纳米的情况，透射率高于90%。考虑到地球表面的太阳辐射，使用眼药水和不使用眼药水时角膜炎形成的阈值时间比分别高于0.93；考虑到弧焊辐射时，该比值高于0.65。
在实际条件下，眼药水的透射光谱未显示出对太阳紫外线辐射的防护作用。然而，在弧焊等人工紫外线源典型的光谱范围内，对UVC辐射有减少作用。我们不建议将这些眼药水用作防护太阳紫外线辐射对眼睛造成损害的紫外线防护辅助剂。
