Barofsky I, Fontaine K R, Cheskin L J
Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Ann Behav Med. 1997 Fall;19(4):408-10. doi: 10.1007/BF02895160.
Obesity is a major public health problem associated with increased health risks, chronic pain, and decrements in functional health status and subjective well-being. To examine the impact of pain on Health-Related Quality-of-Life (HRQL). 312 consecutive persons seeking medically-supervised weight loss treatment completed a sociodemographic questionnaire, the Medical Outcomes Study Short-Form Health Survey (SF-36), and underwent a series of clinical evaluations. Forty-eight percent of the patients when asked to rate "How much pain have you had in the last four weeks?" reported at least moderate pain in the four weeks prior to treatment. In analyses adjusted for sociodemographic factors, body-mass index (BMI) (kg/m2), and depression, obese patients reporting pain scored significantly lower on all SF-36 domains than those not reporting pain. Findings indicate that the pain itself is independently associated with impaired HRQL in nearly half of obese persons seeking treatment. These data demonstrate that pain is a strong covariate of obesity and, therefore, may need to be considered in the design and development of obesity treatments.
肥胖是一个主要的公共卫生问题，与健康风险增加、慢性疼痛以及功能健康状况和主观幸福感下降相关。为了研究疼痛对健康相关生活质量（HRQL）的影响，312名连续寻求医学监督下减肥治疗的人完成了一份社会人口统计学调查问卷、医学结果研究简短健康调查（SF - 36），并接受了一系列临床评估。当被问及“在过去四周内你有多少疼痛？”时，48%的患者报告在治疗前四周至少有中度疼痛。在对社会人口统计学因素、体重指数（BMI）（kg/m²）和抑郁进行调整的分析中，报告有疼痛的肥胖患者在所有SF - 36领域的得分显著低于未报告疼痛的患者。研究结果表明，在近一半寻求治疗的肥胖者中，疼痛本身与受损的HRQL独立相关。这些数据表明疼痛是肥胖的一个强协变量，因此，在肥胖治疗的设计和开发中可能需要考虑这一点。
