Ballenger J C, Davidson J R, Lecrubier Y, Nutt D J, Baldwin D S, den Boer J A, Kasper S, Shear M K
Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston 29425-0742, USA.
J Clin Psychiatry. 1998;59 Suppl 8:47-54.
To provide primary care clinicians with a better understanding of management issues in panic disorder and guide clinical practice with recommendations for appropriate pharmacotherapy.
The 4 members of the International Consensus Group on Depression and Anxiety were James C. Ballenger (chair), Jonathan R. T. Davidson, Yves Lecrubier, and David J. Nutt. Four faculty invited by the chairman also participated: David S. Baldwin, Johan A. den Boer, Siegfried Kasper, and M. Katherine Shear.
The consensus statement is based on the 6 review papers that are published in this supplement and on the scientific literature relevant to these issues.
There were group meetings held during a 2-day period. On day 1, the group discussed each review paper and the chairman and discussant (Dr. Kasper) identified key issues for further debate. On day 2, the group discussed these key issues to arrive at a consensus view. After the group meetings, the consensus statement was drafted by the chairman and approved by all attendees.
The consensus statement provides standard definitions for response and remission and identifies appropriate strategy for the management of panic disorder in a primary care setting. Serotonin selective reuptake inhibitors are recommended as drugs of first choice with a treatment period of 12 to 24 months. Pharmacotherapy should be discontinued slowly over a period of 4 to 6 months.
让基层医疗临床医生更好地理解惊恐障碍的管理问题，并通过适当药物治疗的建议来指导临床实践。
抑郁与焦虑国际共识小组的4名成员分别是詹姆斯·C·巴伦杰（主席）、乔纳森·R·T·戴维森、伊夫·勒克鲁比耶和大卫·J·纳特。主席邀请的4名教员也参与其中：大卫·S·鲍德温、约翰·A·登·布尔、西格弗里德·卡斯珀和M·凯瑟琳·希尔。
该共识声明基于本增刊中发表的6篇综述论文以及与这些问题相关的科学文献。
在为期2天的时间里举行了小组会议。第一天，小组讨论了每篇综述论文，主席和讨论者（卡斯珀博士）确定了需进一步辩论的关键问题。第二天，小组讨论了这些关键问题以达成共识观点。小组会议结束后，由主席起草共识声明并经所有与会者批准。
该共识声明提供了反应和缓解的标准定义，并确定了基层医疗环境中惊恐障碍管理的适当策略。推荐5-羟色胺再摄取抑制剂作为首选药物，治疗期为12至24个月。药物治疗应在4至6个月的时间内缓慢停用。
