Saicic Z S, Pajovic S B, Korac B, Spasic M B, Martinovic J V, Petrovic V M
Department of Physiology, Institute for Biological Research Sinisa Stankovic, Belgrade, Serbia, Yugoslavia.
Physiol Res. 1998;47(1):61-7.
Enzymatic activities of glutathione peroxidase, glutathione-S-transferase, glutathione reductase and catalase, as well as the glutathione content were measured in the brain tissue of regularly cycling rats at dioestrus, proestrus and estrus. The activity of glutathione peroxidase was found to be suppressed at proestrus, whereas that of catalase was increased at dioestrus. Glutathione transferase and glutathione reductase activities, as well as the glutathione content appeared to be stable during the oestrous cycle. These results suggest that, in the female rat, glutathione peroxidase and catalase activities in the brain tissue are influenced by the ovarian hormone status.
在动情间期、动情前期和动情期对正常发情周期大鼠的脑组织进行谷胱甘肽过氧化物酶、谷胱甘肽-S-转移酶、谷胱甘肽还原酶和过氧化氢酶的酶活性以及谷胱甘肽含量的测定。结果发现，谷胱甘肽过氧化物酶的活性在动情前期受到抑制，而过氧化氢酶的活性在动情间期增加。谷胱甘肽转移酶和谷胱甘肽还原酶的活性以及谷胱甘肽含量在发情周期中似乎保持稳定。这些结果表明，在雌性大鼠中，脑组织中的谷胱甘肽过氧化物酶和过氧化氢酶活性受卵巢激素状态的影响。
