Bert F, Bariou-Lancelin M, Lambert-Zechovsky N
Department of Microbiology, Hôpital Beaujon, Clichy, France.
Clin Infect Dis. 1998 Aug;27(2):385-7. doi: 10.1086/514658.
Fifty-one cases of bacteremia due to the "Streptococcus milleri" group were analyzed. Among these were 40 patients with underlying diseases, and associated local infections were present in 27 patients. The most frequent sites of infection were the thoracic cavity and the digestive and hepatobiliary tracts. A probable portal of entry related to mucosal-barrier trauma was identified for an additional 16 patients. The origin of bacteremia was unknown for the remaining eight patients. Abscess formation was evident for only six patients, and there were no cases of endocarditis. Multiple positive blood cultures and polymicrobial bacteremia were associated significantly with the presence of local sites of infection. The most common causative species were Streptococcus anginosus and Streptococcus constellatus. Two patients died of bacteremia.
对51例由“米勒链球菌”群引起的菌血症病例进行了分析。其中40例患者有基础疾病，27例患者存在相关局部感染。最常见的感染部位是胸腔以及消化和肝胆系统。另外16例患者确定了与黏膜屏障创伤相关的可能感染途径。其余8例患者菌血症的来源不明。仅6例患者出现脓肿形成，且无感染性心内膜炎病例。多次血培养阳性和多微生物菌血症与局部感染部位的存在显著相关。最常见的致病菌种是咽峡炎链球菌和星座链球菌。2例患者死于菌血症。
